Catalytic C–H arylation of unactivated heteroaromatics with aryl halides by cobalt porphyrin

Autor:	Ka Lai Wong, Meng Wen Zhang, Ying Ying Qian, Tsz Yiu Kwok, Ching Tat To, Kin Shing Chan
Rok vydání:	2012
Předmět:	Aryl radical Aryl Organic Chemistry chemistry.chemical_element Electrophilic aromatic substitution Biochemistry Porphyrin Medicinal chemistry Homolysis Catalysis chemistry.chemical_compound chemistry Drug Discovery Electrophile Organic chemistry Cobalt
Zdroj:	Tetrahedron Letters. 53:1571-1575
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2012.01.051
Popis:	Direct C–H arylation of unactivated heteroaromatics with aryl halides catalyzed by cobalt porphyrin is reported. The reaction is proposed to go through a homolytic aromatic substitution reaction. The aryl radical is electrophilic and a SOMO–HOMO interaction is predominant in the aryl radical addition process.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::36a72725d3b27456a166a8d1ce506dbc https://doi.org/10.1016/j.tetlet.2012.01.051 Zobrazit plný text záznamu Full Text from ScienceDirect