Metabolic Syndrome as a Factor Affecting on Intima-Media Thickness in Patients with Rheumatoid Arthritis
| Autor: | Anar Akylbecovna Turmuhambetova, Lyudmila Gennadievna Turgunova, Lyazat Kataevna Ibrayeva, Anna Andreevna Shalygina |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
030203 arthritis & rheumatology
medicine.medical_specialty business.industry General Medicine 030204 cardiovascular system & hematology medicine.disease Gastroenterology Disease activity 03 medical and health sciences 0302 clinical medicine Intima-media thickness Internal medicine Rheumatoid arthritis cardiovascular system medicine In patient cardiovascular diseases Metabolic syndrome Statistical processing business |
| Zdroj: | Open Access Macedonian Journal of Medical Sciences. 9:411-416 |
| ISSN: | 1857-9655 |
| DOI: | 10.3889/oamjms.2021.5943 |
| Popis: | AIM: The aim of the study was to assess the association of the thickness of the intima-media complex with metabolic syndrome (MetS) and the degree of disease activity in patients with rheumatoid arthritis (RA). MATERIALS AND METHODS: The study included 101 patients with RA. All patients underwent a biochemical examination, the presence of MetS was determined, and the carotid thickness of the intima-media was determined. Statistical processing was performed using SPSS for Windows, version 18.0. RESULTS: Among 101 patients with RA, 41 (40.5%) had MetS. The frequency of detecting an increased value of the intima-media complex thickness was significantly higher in the group with MetS (n = 31 [75.6%]) than in the group without MetS (n = 21 [35.0%] p ≤ 0.0001). In the group of patients with MetS, the median carotid intima-media thickness (CIMT) was 1.2 mm, while this indicator in the group without MetS was 0.78 mm (U = 727, p = 0.001). In the regression model, MetS (B = 1.05; p = 0.027) and DAS28-ESR (B = 0.506; p = 0.021) were influenced by CIMT. CONCLUSIONS: The results of our study show the effect of MetS and RA activity on the increase of intima-media thickness. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|