Synthesis and rearrangements in the thiazoline imine series

Autor:	N. V. Arkhangel'skaya, M. N. Shchukina, K. M. Murav'eva
Rok vydání:	1970
Předmět:	chemistry.chemical_compound Hydrolysis Aqueous solution Chloroacetone Chemistry Thiazoline Organic Chemistry Imine Organic chemistry Hydrochloric acid
Zdroj:	Chemistry of Heterocyclic Compounds. 3:810-812
ISSN:	1573-8353 0009-3122
Popis:	The rection of 1-acyl-3-(p-ethoxyphenyl)thioureas with chloroacetone or α-bromoacetophenone has given 2-acylimino-3-(pethoxy-phenyl)-4-hydroxy-4-methylthiazolidines or the corresponding 4-phenyl compounds, which readily split out water and are converted into the corresponding acylated 4-thiazolines. The action of aqueous alcoholic hydrochloric acid leads to hydrolysis with the formation of the corresponding 2-imino-3-p-ethoxyphenylthiazolines. When the latter are boiled with 20% hydrochloric acid, they undergo rearrangement to 2-p-ethoxyphenylaminothiazoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3691d0c81c548a098d934fd3cfbdb959 https://doi.org/10.1007/bf00474875 Zobrazit plný text záznamu Full text from SpringerLink