High-resolution footprints of the DNA-binding domain of Epstein-Barr virus nuclear antigen 1

Autor:	A S Kimball, G Milman, T D Tullius
Rok vydání:	1989
Předmět:	HMG-box DNA footprinting Cell Biology DNA-binding domain Biology DNA-binding protein Virology Molecular biology Virus Antigen hemic and lymphatic diseases Epstein–Barr virus nuclear antigen 1 Binding site Molecular Biology
Zdroj:	Molecular and Cellular Biology. 9:2738-2742
ISSN:	1098-5549 0270-7306
Popis:	The DNA-binding domain of Epstein-Barr virus nuclear antigen 1 was found by hydroxyl radical footprinting to protect backbone positions on one side of its DNA-binding site. The guanines contacted in the major groove by the DNA-binding domain of Epstein-Barr virus nuclear antigen 1 were identified by methylation protection. No difference was found in the interaction of the DNA-binding domain of Epstein-Barr virus nuclear antigen 1 with tandemly repeated and overlapping binding sites.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::36906b9719ac3b95b6a226e9cc3fa7b5 https://doi.org/10.1128/mcb.9.6.2738 Zobrazit plný text záznamu