Metallkomplexe mit biologisch wichtigen Liganden. CLXV N,O-Chelat-Komplexe von α-Aminosäureanionen mit cyclopalladiertem N,N-Dimethylferrocencarbothiamid
Autor: | Wolfgang Beck, Karlheinz Sünkel, Thomas Hauck |
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Rok vydání: | 2006 |
Předmět: | |
Zdroj: | Zeitschrift für anorganische und allgemeine Chemie. 632:2305-2309 |
ISSN: | 1521-3749 0044-2313 |
Popis: | Metal Complexes of Biologically Important Ligands. CLXV N,O-Chelate Complexes of α-Amino Acid Anions with Cyclopalladated N,N-Dimethylferrocenecarbothioamide A short literature review on the reactions of various chlorobridged complexes with α-aminoacidates, α-amino acid esters, peptide ester or derivatives of amino acids is given. The chloro bridged o-palladated N,N-dimethylferrocenecarbothioamide [(fct)Pd(μ-Cl)2Pd(fct)] reacts with the anions of glycine, L-alanine, L-proline, L-valine, L-phenylalanine, L-leucine, L-isoleucine to give the N,O-chelates [(fct)Pd(N,O-α-aminocarboxylate)] (1–7). Due to the planary chirality of the unsymmetrically disubstituted cyclopentadienyl iron moiety of fct the complexes 2–7 with optically active amino acidate ligands are formed as a mixture of two diastereoisomers, which can be detected by their NMR spectra. |
Databáze: | OpenAIRE |
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