Metallkomplexe mit biologisch wichtigen Liganden. CLXV N,O-Chelat-Komplexe von α-Aminosäureanionen mit cyclopalladiertem N,N-Dimethylferrocencarbothiamid

Autor:	Wolfgang Beck, Karlheinz Sünkel, Thomas Hauck
Rok vydání:	2006
Předmět:	Inorganic Chemistry chemistry.chemical_classification NMR spectra database chemistry Cyclopentadienyl complex Stereochemistry Diastereomer Moiety chemistry.chemical_element Peptide Chirality (chemistry) Palladium Amino acid
Zdroj:	Zeitschrift für anorganische und allgemeine Chemie. 632:2305-2309
ISSN:	1521-3749 0044-2313
Popis:	Metal Complexes of Biologically Important Ligands. CLXV N,O-Chelate Complexes of α-Amino Acid Anions with Cyclopalladated N,N-Dimethylferrocenecarbothioamide A short literature review on the reactions of various chlorobridged complexes with α-aminoacidates, α-amino acid esters, peptide ester or derivatives of amino acids is given. The chloro bridged o-palladated N,N-dimethylferrocenecarbothioamide [(fct)Pd(μ-Cl)2Pd(fct)] reacts with the anions of glycine, L-alanine, L-proline, L-valine, L-phenylalanine, L-leucine, L-isoleucine to give the N,O-chelates [(fct)Pd(N,O-α-aminocarboxylate)] (1–7). Due to the planary chirality of the unsymmetrically disubstituted cyclopentadienyl iron moiety of fct the complexes 2–7 with optically active amino acidate ligands are formed as a mixture of two diastereoisomers, which can be detected by their NMR spectra.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3672a20ee429473a46f91bf496a0ce1c https://doi.org/10.1002/zaac.200600177 Zobrazit plný text záznamu Plný text