Investigation of numerical models for planning of electrochemotherapy treatments of invasive ductal carcinoma
Autor: | L. Leija-Salas, Damijan Miklavčič, C. E. Vera-Tizatl, A. Vera-Hernandez, A. L. Vera-Tizatl, S. A. Rodriguez-Cuevas, Bor Kos |
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Rok vydání: | 2017 |
Předmět: |
Electrochemotherapy
Computer science 0206 medical engineering Numerical modeling 02 engineering and technology Numerical models Invasive ductal carcinoma 020601 biomedical engineering Interpolation function 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Boundary value problem Biomedical engineering Interpolation |
Zdroj: | 2017 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges (GMEPE/PAHCE). |
Popis: | Three numerical models are presented in this work i. e., a reference model and interpolated models varying geometrical traits, material properties, boundary conditions and mesh size to establish their effects in the resultant electric field during electrochemotherapy. For static conductivity the results show that the use of an interpolation function grid of 1 mm and a normal mesh are suitable for further more complex models. On the other hand an iterative increasing conductivity behavior describes better the increasing conductivity phenomenon reported to be caused by electroporation. The results reported in this work could be useful in further modeling of breast tumors and development of treatment planning for electrochemotherapy based on invasive ductal carcinoma. |
Databáze: | OpenAIRE |
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