Autor:	Toyonari Oine, Kazuhiko Kondo, Kentaro Okumura, Ichizo Inoue
Rok vydání:	1974
Předmět:	chemistry.chemical_compound Chemistry Aryl Drug Discovery Chromone Organic chemistry General Chemistry General Medicine Combinatorial chemistry Acetanilide
Zdroj:	Chemical and Pharmaceutical Bulletin. 22:331-336
ISSN:	1347-5223 0009-2363
DOI:	10.1248/cpb.22.331
Popis:	Several chromone-3-carboxanilides (7a-f) were prepared by amidation of chromone-3-carboxylic acid (6), or better, by cyclization of 2- (2-hydroxybenzoyl) acetanilides (9a-c). In the latter procedure, the direct and convenient synthesis of 2- (2-benzyloxybenzoyl) -acetanilides (8a and 8b) from 2-benzyloxyacetophenone (1) was achieved using aryl isocyanates in the presence of NaH.
Databáze:	OpenAIRE
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