A mechanistic study of thiol addition to N-acryloylpiperidine
| Autor: | Sarah K. I. Watt, Janique G. Charlebois, Christopher N. Rowley, Jeffrey W. Keillor |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Organic & Biomolecular Chemistry. 21:2204-2212 |
| ISSN: | 1477-0539 1477-0520 |
| Popis: | A kinetic study of the reaction mechanism of the thiol addition reaction of the acryloyl piperidine ‘warhead’ reveals its intrinsic reactivity and thiol sensitivity, which are relevant to inhibitor design. |
| Databáze: | OpenAIRE |
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