Chromosomal aberrations induced by Markhamia tomentosa (Benth.) K. Schum. Ex Engl. ethanolic leaf extract on Allium cepa root cells

Autor: Abimbola Sowemimo, Mutiat B. Ibrahim, Olukemi A. Odukoya
Rok vydání: 2015
Předmět:
Zdroj: Nigerian Journal of Natural Products and Medicine. 18:12
ISSN: 1118-6267
DOI: 10.4314/njnpm.v18i1.3
Popis: Markhamia tomentosa (Benth.) K. Schum. Ex Engl. (Bignoniaceae) is used traditionally in the treatment of pain, oedema, pulmonary troubles and cancer. The genotoxic and cytotoxic effects of the ethanolic extract of the leaves of M. tomentosa was investigated using the Allium cepa root chromosomal aberration assay. The mitotic index, chromosomal aberrations and mean root length effects of the plant extract on onion bulbs were determined using 50, 100, 200, 400 and 1000 μg/ml concentrations of the plant extract. Tap water was used as the negative control. The result showed a significant (p
Databáze: OpenAIRE