Acquired Resistance to Antibiotics: An Underestimated Cause of Failure in the Treatment of Helicobacter pylori Infection

Autor: Y. Glupczynski, A. Burette
Rok vydání: 1991
Předmět:
Zdroj: Helicobacter pylori 1990 ISBN: 9783642757280
Popis: There is now overwhelming evidence that Helicobacter pylori is the major etiological agent of chronic active (type B) gastritis and that it may further predispose to peptic ulceration. Challenge studies in gnotobiotic piglets and in two human volunteers have reproduced the typical features of gastritis [16, 17, 21, 29]. Clearance of the organism with amoxycillin, furazolidone, or bismuth salts leads to improvement or even total resolution of gastritis [7, 25, 28, 32]. Moreover, several studies have shown that patients with healed peptic ulcer who remain persistently infected with H. pylori relapse much more frequently than patients cleared of the organism [3, 22].
Databáze: OpenAIRE