Incidence and predictors of hypertension during high-dose dexmedetomidine sedation for pediatric MRI
| Autor: | Paulette J. Fontaine, Randy Prescilla, Steven E. Zgleszewski, David Zurakowski, James A. DiNardo, Keira P. Mason |
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| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Pediatric Anesthesia. 20:516-523 |
| ISSN: | 1460-9592 1155-5645 |
| DOI: | 10.1111/j.1460-9592.2010.03299.x |
| Popis: | Summary This study reviewed the hypertensive response of a large population of children to high-dose dexmedetomidine sedation with the aim of determining the incidence and predictors of hypertension. Background: When dexmedetomidine is used to provide sedation for children, fluctuations in blood pressure have been described in case reports. We report the incidence and predictors of hypertension in a large series of children who received dexmedetomidine. Methods/Materials: At our institution, a computerized database holds patient demographics, sedation outcomes, adverse events, and hemodynamic data for all children who receive dexmedetomidine sedation for radiological imaging studies. After Institutional Review Board approval, this database was reviewed. Results: Three thousand five hundred twenty-two (3522) children received dexmedetomidine sedation between May 1, 2007 and December 31, 2008 for magnetic resonance imaging studies. Median age was 3.6 years (interquartile range: 1.8–5.9). A total of 172 patients (4.9%) developed hypertension, with a higher incidence in the younger age group (0–3 years) when compared to the older age groups (3–18 years) (P |
| Databáze: | OpenAIRE |
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