Structure and Assembly of the Escherichia coli Ribosome

Autor:	G.W. Tischendorf, H.G. Wittman, K.H. Nierhaus, G. Stöffler, G. Sieber, B. Tesche, B. Wittman-Liebold
Rok vydání:	1978
Předmět:	0303 health sciences 03 medical and health sciences Biochemistry Chemistry 020209 energy 0202 electrical engineering electronic engineering information engineering medicine 02 engineering and technology General Medicine medicine.disease_cause Ribosome Escherichia coli 030304 developmental biology
Zdroj:	Proceedings, annual meeting, Electron Microscopy Society of America. 36:459-469
ISSN:	2690-1315 0424-8201
DOI:	10.1017/s0424820100070187
Popis:	Biosynthesis of proteins takes place on ribosomes which are multi-component particles occurring in all organisms. There are two classes of ribosomes in nature: the 80S ribosomes present in the cytoplasm of eukaryotic cells and the 70S ribosomes in prokaryotes. Ribosomes in chloroplasts and mitochondria are related to the prokaryotic ribosomes, although their sedimentation coefficients differ in many cases from 70S.ComponentsThe best known ribosome is that of the bacterium E. coli. It consists of two subunits of unequal size (30S and 50S). Besides three RNA molecules (5S, 16S and 23S) there are many ribosomal proteins. Their number was first determined by two-dimensional polyacrylamide electrophoresis.
Databáze:	OpenAIRE
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