Investigation of the Relationship Between Occupational Stress and Temporomandibular Joint Disorders by Measuring Salivary Cortisol and Immunoglobulin a Levels in Students of Qom Dental School

Autor: Elham Keykha, Yasamin Barakian, Alireza Karimi, Abolfazl Mohammadbeigi, Samira Hajisadeghi
Rok vydání: 2021
Předmět:
DOI: 10.21203/rs.3.rs-440266/v1
Popis: Objectives Occupational stress is defined as a lack of coordination between job requirements and individual abilities. This stress relates to several salivary biomarkers. Stress plays an important role in creating temporomandibular disorder (TMD). In this study we aimed to investigate the relationship between stress and TMD by examining the occupational stress using dental environment stress (DES) questionnaire and measuring the stress markers in saliva including cortisol and immunoglobulin A in fourth to sixth year students of Qom Dental School. Methods In present study, 60 students participated. At first, a clinical examination was performed based on the RDC/TMD method to determine the temporomandibular joint status, then a DES questionnaire was completed to determine the occupational stress level and finally a sample of saliva was taken from the students and the amounts of salivary cortisol and IgA were measured by enzyme-linked immunosorbent assay (ELISA). Results The mean cortisol and IgA levels were 4.74 ± 2.80 ng/ml and 220.26 ± 121.22 µg/ml, respectively and the mean score of the DES questionnaire was 2.48 ± 0.58. In this study, 24 patients (40%) suffered from TMD. There was no correlation between cortisol and IgA levels with the DES score (p value > 0.05). There was no significant relationship between TMD and three variables of cortisol, IgA and DES scores (p value > 0.05). Conclusion Stress is one of the most important causes of TMD. Salivary biomarkers can be useful markers for determining stress in people with TMD but this issue was not confirmed in our study. Clinical relevance: In this study, no relationship was observed between TMD and occupational stress.
Databáze: OpenAIRE