Characteristics and outcomes of pace mapping for ablation of premature ventricular complexes

Autor:	H A Hauer, M.J.B Kemme, M J Mulder, C P Allaart, R Ozer, Giovanni J.M. Tahapary, E.M Van Zutphen
Rok vydání:	2020
Předmět:	Premature ventricular complexes medicine.medical_specialty Ejection fraction business.industry medicine.medical_treatment 12 lead ecg Cardiac arrhythmia Gold standard (test) Cardiac Ablation Ablation Internal medicine medicine Cardiology Cardiology and Cardiovascular Medicine business Pace mapping
Zdroj:	European Heart Journal. 41
ISSN:	1522-9645 0195-668X
Popis:	Background/Introduction Activation mapping is the “gold standard” for localisation of the site of origin during mapping and ablation of symptomatic premature ventricular complexes (PVC). In case of suppression of PVCs during the procedure, the origin of the PVC can be located using a pace mapping technique. The PASO module is an addition in the CARTO3 mapping system that calculates the correlation between the induced and observed 12-lead ECG PVC morphology, and visualises this correlation on an isochronal 3D colour map. Purpose The aim of this study was to compare the follow-up success rate of pace mapping using the PASO module and activation mapping and to determine cut-off values for clinical success. Methods Seventy-six consecutive ablation procedures of symptomatic PVCs were included in this single-center retrospective study. Mapping and ablation parameters were derived from the CARTO3 mapping system. Ablation success was defined as a ≥95% reduction in PVC burden on 24-hour Holter recordings or absence of the clinical PVC on multiple ECGs in case of multiple PVC morphologies. Logistic regression analysis was performed to evaluate the relationship between applied mapping methods and ablation parameters. Optimal cut-off values of ablation characteristics for successful ablation were determined using ROC curves. Results Thirty-five (46%) patients were male and 39 (51%) patients had a reduced left ventricular ejection fraction. Pace mapping was used in 36 (47%) patients. Baseline PVC burden was lower in patients when pace mapping was applied (18% vs. 28%, p Conclusion This study indicates that pace mapping using PASO is a good alternative for activation mapping for localisation of the PVC. A minimum PASO correlation coefficient of 97.6% is the optimal cut-off value for successful PVC ablation. ROC of maximum PASO coefficient Funding Acknowledgement Type of funding source: None
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::36023a5e8cc87371da15895ae49386e5 https://doi.org/10.1093/ehjci/ehaa946.0419 Zobrazit plný text záznamu