Mycoplasma genitalium:prevalence in men presenting with urethritis to a South Australian public sexual health clinic
| Autor: | Robert M Douglas, Tonia Mezzini, Tania Sadlon, Russell Waddell |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Gynecology
medicine.medical_specialty Sexual health clinic biology business.industry bacterial infections and mycoses urologic and male genital diseases medicine.disease biology.organism_classification medicine.disease_cause female genital diseases and pregnancy complications Men who have sex with men Internal medicine Epidemiology Internal Medicine medicine Neisseria gonorrhoeae Dysuria Urethritis medicine.symptom Mycoplasma genitalium business Chlamydia trachomatis |
| Zdroj: | Internal Medicine Journal. 43:494-500 |
| ISSN: | 1444-0903 |
| DOI: | 10.1111/imj.12103 |
| Popis: | Background/Aim This study aimed to determine the prevalence of Mycoplasma genitalium infection among male patients with dysuria and/or urethral discharge. An analysis of the clinical, demographic and microbiological factors associated with M. genitalium infection was also conducted. Method From May 2007 to June 2011, men presenting to the clinic with self-reported symptoms of dysuria and/or urethral discharge were identified and underwent urethral swab, which was microscopically assessed for objective non-gonococcal urethritis. A first-void urine sample was tested for Chlamydia trachomatis and Neisseria gonorrhoeae using the Aptima Combo-2 assay. A portion of the urine sample was sent for polymerase chain reaction analysis for M. genitalium. Results One thousand, one hundred and eighty-two men with dysuria and/or urethral discharge were tested for M. genitalium. Of those, 96 men (8.1%) were positive for M. genitalium. Men identifying as solely MSM (men who have sex with men) constituted 16.3% (n = 193) of the sample. Their infection rate was 3.1% (n = 6). The infection rate for heterosexual and bisexual men was 9.1%. For all men, the M. genitalium co-infection rate was 14.6% (n = 14) with C. trachomatis and 3.1% (n = 3) with N. gonorrhoeae. Factors associated with M. genitalium infection were analysed by univariate analysis. We determined that five investigated predictors were significantly associated with M. genitalium infection, urethral discharge, non-gonococcal urethritis on Gram stain of urethral smears, identification as heterosexual or bisexual, and absence of co-infection with C. trachomatis or N. gonorrhoeae. Conclusion In Adelaide, M. genitalium is an important sexually transmitted infection among men with dysuria and/or urethral discharge, and is primarily an infection of heterosexual and bisexual men. |
| Databáze: | OpenAIRE |
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