Tailoring Sol–Gel-Derived Silica Materials for Optical Biosensing
| Autor: | Maria Rowena N. Monton, Erica M. Forsberg, John D. Brennan |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
Materials science General Chemical Engineering Aptamer Biomolecule technology industry and agriculture Deoxyribozyme Nanotechnology General Chemistry engineering.material chemistry Coating Materials Chemistry engineering Bioactive paper Contact print Biosensor Sol-gel |
| Zdroj: | Chemistry of Materials. 24:796-811 |
| ISSN: | 1520-5002 0897-4756 |
| Popis: | The last two decades have seen a revolution in the area of sol–gel-derived materials as media for the immobilization of biomolecules for biosensor fabrication. Such materials are suitable for the entrapment of a range of biomolecules, from enzymes to antibodies and even functional nucleic acids (FNA) such as aptamers and DNA enzymes. Recent progress in the development of “protein friendly” sol–gel processing methods has allowed these materials to be utilized as components of numerous biosensors, using delicate biomolecules such as luciferease and kinases, or even membrane-bound receptors as biorecognition elements. In addition, such materials have proven to be particularly versatile in the fabrication of biosensors, being amenable to methods such as dipcasting, contact printing, or even noncontact inkjet printing to form a bioselective coating on a range of substrates. In this review, we provide an overview of advances in biofriendly sol–gel processing methods developed in our research group and others, a... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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