Perl and Python codes to estimate Hardy–Weinberg- and linkage-disequilibrium-related parameters
Autor: | Julianno B. M. Sambatti, Brad Sickler |
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Rok vydání: | 2006 |
Předmět: |
Discrete mathematics
Linkage disequilibrium Ecology Correlation coefficient Biology Lambda Bioinformatics Quantitative Biology::Genomics Biochemistry Hardy–Weinberg principle General Biochemistry Genetics and Molecular Biology Quantitative Biology::Populations and Evolution natural sciences Perl computer computer.programming_language |
Zdroj: | Molecular Ecology Notes. 6:594-596 |
ISSN: | 1471-8286 1471-8278 |
DOI: | 10.1111/j.1471-8286.2006.01374.x |
Popis: | We have developed two pieces of Perl and Python codes to calculate the natural log of lambda, a quantity that expresses deviations from Hardy–Weinberg equilibrium, and R, a weighted correlation coefficient between alleles of locus pairs as a quantity that expresses linkage disequilibrium. These quantities can be used in an estimation approach as tools to facilitate the characterization and the comparison of populations. |
Databáze: | OpenAIRE |
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