Enantioselective Olfactory Effects of the Neonicotinoid Dinotefuran on Honey Bees (Apis mellifera L.)
| Autor: | Sihong Liu, Fengmei He, Huihua Tan, Xuesheng Li, Yanmei Liu, Hui Zhang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
digestive oral and skin physiology fungi 010401 analytical chemistry Neonicotinoid food and beverages General Chemistry Honey bee Olfaction Pesticide Biology complex mixtures 01 natural sciences Dinotefuran 0104 chemical sciences chemistry.chemical_compound Honey Bees chemistry Biochemistry Toxicity behavior and behavior mechanisms Octopamine (neurotransmitter) General Agricultural and Biological Sciences 010606 plant biology & botany |
| Zdroj: | Journal of Agricultural and Food Chemistry. 67:12105-12116 |
| ISSN: | 1520-5118 0021-8561 |
| DOI: | 10.1021/acs.jafc.9b04851 |
| Popis: | Sublethal exposure to neonicotinoids affects honey bee olfaction, but few studies have investigated the sublethal effects of the enantioselective neonicotinoid dinotefuran on honey bee olfaction. This study assessed the sublethal olfactory toxicity of dinotefuran enantiomers to honey bees. Compared to R-dinotefuran, S-dinotefuran had higher acute oral toxicity, sucrose sensitivity effects, octopamine concentrations, lower learning ability, and memory effects on honey bees. High-throughput circular RNA sequencing of the honey bee brain revealed that R-dinotefuran caused more gene regulatory changes than S-dinotefuran. Gene ontology enrichment and Kyoto Encyclopedia of Genes and Genomes pathway analyses demonstrated that the SERCA, Kca, and Maxik genes may be related to the enantioselective effects of dinotefuran isomers on honey bee olfaction. These results indicated that the current ecotoxicological safety knowledge about chiral dinotefuran effects on honey bees should be amended. |
| Databáze: | OpenAIRE |
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