Association of Baseline urodynamic measures of urethral function with clinical, demographic, and other urodynamic variables in women prior to undergoing midurethral sling surgery

Autor: Jan Baker, Toby C. Chai, Liyuan Huang, Stephen R. Kraus, Kim Kenton, Holly E. Richter, Heather J. Litman
Rok vydání: 2012
Předmět:
Zdroj: Neurourology and Urodynamics. 31:496-501
ISSN: 0733-2467
DOI: 10.1002/nau.21198
Popis: Aims—To explore how baseline demographic, clinical and urodynamic variables correlate with measures of urethral function in women planning midurethral sling surgery. Methods—Women with predominant stress urinary incontinence (SUI) as part of the Trial of Mid-Urethral Slings (TOMUS) were characterized preoperatively including: demographics, body mass index (BMI), responses to the Medical and Epidemiologic Social Aspects of Aging (MESA) and Urogenital Distress Inventory (UDI) questionnaires, pad weight (PW), incontinence duration, prior SUI surgery, prolapse, strength of pelvic contraction, Q-tip test, uroflow, cystometrogram and detrusor pressures at maximum flow (Pdet at Qmax). Multivariate regression analysis and modeling confirmed variables with significant correlations with maximal urethral closure pressure (MUCP), functional urethral length (FUL) and Valsalva leak point pressure (VLPP). Results—Five-hundred thirty nine women were included in the analysis. In multivariable analyses, PW (p=0.045) and age (p
Databáze: OpenAIRE