Kinetics of the aza-Michael Reaction at Room Temperature

Autor:	E. V. Koverzanova, I. I. Levina, A. A. Gridnev
Rok vydání:	2018
Předmět:	010405 organic chemistry Chemistry Kinetics Substituent 010402 general chemistry Methacrylate 01 natural sciences Medicinal chemistry 0104 chemical sciences Reaction rate chemistry.chemical_compound Reaction rate constant Michael reaction Methanol Physical and Theoretical Chemistry Acrylonitrile
Zdroj:	Russian Journal of Physical Chemistry B. 12:46-52
ISSN:	1990-7923 1990-7931
DOI:	10.1134/s1990793118010219
Popis:	The rates of the aza-Michael reaction at room temperature were measured for some amines and alkenes. When the reaction mixture was diluted with methanol, the reaction was accelerated. The acceleration with methanol was especially strong for acrylonitrile. In the latter case, the reaction rate constant can increase by almost three decimal orders. The bulky substituent in the alpha position of methacrylates had little effect on the reaction rate, while the bulky substituent in the ester group significantly slowed the aza-Michael reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::353a2ae087e1a875c0f32179d08aa6e0 https://doi.org/10.1134/s1990793118010219 Zobrazit plný text záznamu Full text from SpringerLink