Divergent Synthesis of Enantioenriched β-Functional Amines via Desymmetrization of meso-Aziridines with Isocyanides

Autor:	Xiaohua Liu, Xiangqiang Li, Xiaoming Feng, Mingming Guan, Qian Xiong, Shunxi Dong
Rok vydání:	2019
Předmět:	010405 organic chemistry Stereochemistry Chemistry Organic Chemistry Enantioselective synthesis Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Biochemistry Divergent synthesis Desymmetrization 0104 chemical sciences
Zdroj:	Organic Letters. 21:6096-6101
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.9b02242
Popis:	A highly enantioselective ring-opening desymmetrization of meso-aziridines with isocyanides was achieved in the presence of a chiral N,N′-dioxide/Mg(OTf)2 complex. The in situ generated chiral 1,4-...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::34eef679eb504d1addbad611df26d9bb https://doi.org/10.1021/acs.orglett.9b02242 Zobrazit plný text záznamu