Impact of Contrast Agent Viscosity on Coronary Balloon Deflation Times: Bench Testing Results

Autor:	Tesfaldet T. Michael, Vishal G. Patel, Owen Mogabgab, George Christopoulos, Subhash Banerjee, Emmanouil S. Brilakis, Anna Kotsia
Rok vydání:	2014
Předmět:	medicine.medical_specialty business.industry media_common.quotation_subject medicine.medical_treatment Ioxaglic acid Balloon Iodixanol Deflation Internal medicine Anesthesia medicine Cardiology Contrast (vision) Cineangiography Radiology Nuclear Medicine and imaging Cardiology and Cardiovascular Medicine business Saline Syringe medicine.drug media_common
Zdroj:	Journal of Interventional Cardiology. 27:177-181
ISSN:	0896-4327
DOI:	10.1111/joic.12097
Popis:	Objectives To assess the impact of viscosity on angioplasty balloon deflation times. Background Lower contrast viscosity could result in more rapid coronary balloon deflation times. Methods We performed a bench comparison of coronary balloon deflation times using 2 contrast agents with different viscosity (ioxaglate and iodixanol), 3 contrast dilutions, and 2 inflation syringe filling volumes. Ten identical pairs of coronary angioplasty balloons were used to conduct each comparison after balloon inflation to 12 atmospheres. Simultaneous deflations were performed under cineangiography. The time to full contrast extraction and the area of contrast remaining after 5 seconds of deflation (quantified by opaque pixel count) were compared between groups. Results The mean time to full contrast extraction during balloon deflation was 8.3 ± 2.5 seconds for ioxaglate (lower viscosity) versus 10.1 ± 2.9 seconds for iodixanol (higher viscosity) (17.4% decrease, P = 0.005), with a 35.6% (P = 0.004) reduction in contrast area at 5 seconds. Compared to 1:1 ioxaglate–saline mixture, 1:2 and 1:3 ioxaglate/saline mixes resulted in 26.7% (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::34e722e51fd94db5f3476069dc70a655 https://doi.org/10.1111/joic.12097 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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