| Autor: |
J. A. Mollenhauer, K. D. Jandt, P. Hortschansky |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
Ceramics in Orthopaedics ISBN: 9783798516342 |
| DOI: |
10.1007/978-3-7985-1635-9_42 |
| Popis: |
Bone Morphogenetic Proteins (BMP) induce and propagate skeletal wound healing. They enable osteoinductive mechanisms. Applied in combination with osteoconductive solid implant materials, BMP might accelerate and enhance bone regeneration even in individuals with compromised bone metabolism, such as osteoporotic or elderly patients. Presently, soluble BMP released from rapidly degrading carriers such as collagen is favored. Here we present structural and functional aspects of bioactivity from small quantities of implant surface-fixed BMP, potentially resulting in a more controlled topical action. Solid implants such improved may prevent untoward effects from overdosing and may exhibit better storage properties than present preparations of BMP. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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