Novel synthesis of 1,4-benzothiazines in water accelerated by β-cyclodextrin
Autor: | Sudhakar L. Padwal, Ramrao A. Mane, Manisha R. Bhosale, Balaji S. Londhe |
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Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Journal of the Iranian Chemical Society. 13:443-447 |
ISSN: | 1735-2428 1735-207X |
Popis: | Novel one-pot synthetic protocol has been developed for obtaining 2, 3-disubstituted 1,4-benzothiazines with excellent yields, carrying cyclocondensation of 1,3-dicarbonyl compounds with substituted 2-(2-(2-aminophenyl)disulfanyl)benzenamines, under supramolecular catalysis of β-Cyclodextrin (β-CD) in water at neutral pH. The role of β-CD in accelerating the cyclocondensation has been demonstrated. This biomimic catalyzed route is simple, economic, relatively rapid and environmentally benign. |
Databáze: | OpenAIRE |
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