ChemInform Abstract: Lithium Benzenetellurolate-Induced Reformatsky-Type Reaction in the Presence of Cerium Trichloride

Autor:	Katsuhiko Hirai, Shin-ichi Fukuzawa
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Steric effects Ketone chemistry.chemical_element General Medicine Condensation reaction Medicinal chemistry Benzaldehyde Cerium chemistry.chemical_compound chemistry Reagent Lithium Stereoselectivity
Zdroj:	ChemInform. 24
ISSN:	0931-7597
DOI:	10.1002/chin.199351076
Popis:	Reformatsky-type reactions with PhTeLi in the presence of CeCl3 proceeded smoothly under mild conditions. The PhTeLi–CeCl3 reagent was particularly efficient for the reactions of sterically hindered and enolizable ketones; in the absence of CeCl3 unsatisfactory yields of the desired β-hydroxy ketone were obtained. It is assumed that CeCl3 reactions involve a cerium enolate intermediate. The stereoselectivity of the reaction between ethyl 2-bromopropionate and benzaldehyde is also described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::34ccf20eeca1ab410bb92b8c9ab75f4f https://doi.org/10.1002/chin.199351076 Zobrazit plný text záznamu Plný text