An approach to new chiral bicyclic imines and amines via Horner–Wadsworth–Emmons reaction

Autor:	Elżbieta Wojaczyńska, Marcin Górecki, Mateusz Sowiński, Jakub Iwanejko, Tomasz K. Olszewski
Rok vydání:	2020
Předmět:	chemistry.chemical_compound chemistry Bicyclic molecule General Chemical Engineering High selectivity Horner–Wadsworth–Emmons reaction Substrate (chemistry) General Chemistry Phosphonate Combinatorial chemistry Carbanion
Zdroj:	RSC Advances. 10:14618-14629
ISSN:	2046-2069
DOI:	10.1039/d0ra02646h
Popis:	New chiral bicyclic imines, enamines and amines were prepared via Horner–Wadsworth–Emmons reaction of hexahydroquinoxalin-2(1H)-one-derived phosphonate, as the source of a phosphonate carbanion, and a wide range of structurally diverse carbonyl substrates. The simplicity of the synthetic protocol, high selectivity, and broad substrate scope are the main advantages of the presented methodology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3491360d545d745e92959908dd549bc5 https://doi.org/10.1039/d0ra02646h Zobrazit plný text záznamu