Synthesis, Characterization and Crystal Structure of 2-Pyridinecarboxamide

Autor:	Kai-Jin Sun, Zhao-Sheng Cai
Rok vydání:	2019
Předmět:	Crystallography Chemistry General Chemistry Crystal structure Characterization (materials science)
Zdroj:	Asian Journal of Chemistry. 32:195-198
ISSN:	0975-427X 0970-7077
Popis:	2-Pyridinecarboxamide was synthesized from 2-picoline through two-steps reaction. Initially, 2-picoline was converted into 2-cyanopyridine by ammoxidation in a stainless-steel fixed-bed reactor at 370 ºC with V2O5 loaded on TiO2 as catalyst. The 2-cyanopyridine was transformed into 2-pyridinecarboxamide through oxidation hydrolysis in basic solution using MnO2 as oxidant at 70 ºC. The final product was characterized by FT-IR, NMR and UV-visible analysis, and 2-pyridinecarboxamide in the final product was determined using HPLC. The crystal structure of 2-pyridinecarboxamide was investigated using X-ray diffraction and SHELX 2018/3 (sh) software and the result indicated that 2-pyridinecarboxamide crystallized in the monoclinic system, space group P21/n with a = 5.207(2), b = 7.097(3), c = 16.243(6) Å, V = 595.7 (4) Å3; Z = 4.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::349087e8d25808bb4622f2a3e73e89a0 https://doi.org/10.14233/ajchem.2020.22395 Zobrazit plný text záznamu