A Substitution-Dependent Light-Up Fluorescence Probe for Selectively Detecting Fe3+ Ions and Its Cell Imaging Application
| Autor: | Xuewen He, Zheng Zhao, Ying Li, Ryan T. K. Kwok, Xing Feng, Jacky Wing Yip Lam, Haixiang Liu, Ben Zhong Tang, Mark R. J. Elsegood |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Analyte
Materials science Substituent 02 engineering and technology Tetraphenylethylene 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Photochemistry 01 natural sciences Fluorescence Acid dissociation constant 0104 chemical sciences Electronic Optical and Magnetic Materials Biomaterials chemistry.chemical_compound Molecular recognition chemistry Electrochemistry 0210 nano-technology Molecular probe Selectivity |
| Zdroj: | Advanced Functional Materials. 28:1802833 |
| ISSN: | 1616-301X |
| Popis: | Deliberate design of specific and sensitive molecular probes with distinctive physical/chemical properties for analyte sensing is of great significance. Herein, by taking advantage of the position-dependent substituent effects, an aggregation-induced emission featured iron (III) probe from ortho-substituted pyridinyl-functionalized tetraphenylethylene (TPE-o-Py) is synthesized. It displays high sensitivity and selectivity toward iron (III) detection. The recognition arises from the position isomer of ortho-substitution, and the fact that TPE-o-Py has a low acid dissociation constant (pKa) that is close to that of hydrolyzed Fe3+. Importantly, TPE-o-Py as a light-up fluorescence probe could be employed for Fe3+sensing in living cells with a pronounced red-shift in fluorescence emission. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text