Synthesis of 3,4-dihydrothioxanthene-1,9-dione analogs as potential antimalarial agents
Autor: | Dennis Joseph Mcnamara, Leslie M. Werbel, Hung Jocelyn H |
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Rok vydání: | 1983 |
Předmět: | |
Zdroj: | Journal of Heterocyclic Chemistry. 20:1575-1580 |
ISSN: | 1943-5193 0022-152X |
Popis: | 7-Chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1H-thioxanthene-1,9 (2H)-dione (10), and a variety of analogs and derivatives were prepared as sulfur isosteric analogs of the acridinedione antimalarial agent, floxacrine. The compounds were devoid of antimalarial activity against P. berghei in mice. |
Databáze: | OpenAIRE |
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