wirkung von UV-C und von 8-MOP + UV-A auf die T- und B-Population menschlicher lymphocyten in vitro

Autor:	G. Bächtold, Gerd Lischka, Elisabeth Bohnert, Ernst G. Jung
Rok vydání:	1977
Předmět:	education.field_of_study Chemistry Lymphocyte Population Dermatology General Medicine Molecular biology In vitro Thymidine incorporation Transformation (genetics) medicine.anatomical_structure Rosette formation medicine Irradiation education Incubation
Zdroj:	Archives for Dermatological Research. 260:63-70
ISSN:	1432-069X 0340-3696
Popis:	The transformation of UV-C irradiated leucocytes and lymphocytes by the mitogens Con A, PHA and PWM is measured by the3H-Tdr. incorporation after 72 h incubation. Furthermore T-and B-cells are determined by the method of rosette formation. A clear inhibition of the cell activity is seen after irradiation of leucocytes with 450 mJ/cm2 and of a lymphocyte suspension with 5–10 mJ/cm2. There are no significant differences between the effects of the various mitogens. The number of T-cells decreases proportionality to the various intensity, the number of B-cells remain constant. Irradiation with UV-A + 8-MOP cause, equaly for all mitogens, a dosis dependent inhibition of thymidine incorporation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::347cd9235882a19ab074df8745dfd0cb https://doi.org/10.1007/bf00558016 Zobrazit plný text záznamu Full text from SpringerLink