Short- and Long-Term Growth as a Function of Abnormal Doppler Flow in Growth-Restricted Fetuses
| Autor: | A. George Neubert, Michael J. Paglia, A. Dhanya Mackeen, Wen Feng, John W. Ross, Alexandria Betz |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Fetus 030219 obstetrics & reproductive medicine Long term growth business.industry Short term growth Cardiac surgery Paediatric cardiology 03 medical and health sciences 0302 clinical medicine Doppler flow Internal medicine medicine Cardiology 030212 general & internal medicine Neonatology business |
| Zdroj: | Prenatal Cardiology. 8:76-79 |
| ISSN: | 2353-8201 |
| DOI: | 10.1515/pcard-2018-0012 |
| Popis: | OBJECTIVES: To evaluate short- and long-term growth in fetuses with growth restriction (FGR) and elevated umbilical artery Doppler (UAD) systolic/diastolic (S/D) ratios. METHODS: In this prospective observational study, two UAD waveforms were obtained from each umbilical artery weekly and were classified as normal or abnormal. Fetal growth was assessed every 3 weeks. Short-term growth was calculated from the first visit with elevated ratios until next growth assessment. Results were grouped by number of initial elevated S/D ratios (maximum, 4). Long-term growth was evaluated by change in estimated fetal weight from diagnosis of FGR to birth weight. Fetuses were grouped by average number of elevated S/D ratios and compared to a reference population of growth restricted fetuses with normal testing. RESULTS: Of 241 fetuses evaluated, 105 demonstrated elevated S/D ratios. Short-term growth was impaired when fetuses had elevated S/D ratios. Long-term growth was affected when the average number of elevated S/D ratios was ≥1 per visit. Progressive 3 or 4 growth delay was noted as the average number of abnormal S/D ratios increased. CONCLUSIONS: Short- and long-term fetal growth are affected by elevated UAD S/D ratios. Fetuses with more abnormal values initially and those with a higher average of elevated values over pregnancy demonstrate decreased growth. |
| Databáze: | OpenAIRE |
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