Allosteric ATPase behavior: the onset of laser-sustained enzyme cooperation

Autor: Lorenzo Bolognani, F. Causa, Michele Costato, Marziale Milani
Rok vydání: 1995
Předmět:
Zdroj: SPIE Proceedings.
ISSN: 0277-786X
DOI: 10.1117/12.197473
Popis: A two level model is considered to describe the dynamics of a biological system undergoing cyclic oscillations from one state to another separated by an energy quantum interval. This is typically met in enzyme activated reactions, involving the ADP-ATP cycle. General results can be obtained analytically, the dynamics of the system being investigated from an energetic point of view. Numerical solutions show how an enzymatic system can be driven across different regimes where cooperation (allostericity) and oscillations appears. The model can be extended to the case of an external energy supply in the form of electromagnetic radiation, providing clues for a physical understanding of nonthermal laser interaction with biosystems.
Databáze: OpenAIRE