Determination of a trivariate reference region for free thyroxine index, free triiodothyronine index, and thyrotropin from results obtained in a health survey of middle-aged women

Autor:	B Kågedal, A Sandström, G Tibbling
Rok vydání:	1978
Předmět:	Mahalanobis distance medicine.medical_specialty Index (economics) Triiodothyronine business.industry Free thyroxine index Biochemistry (medical) Clinical Biochemistry Univariate Endocrinology Internal medicine Free triiodothyronine Statistics medicine Health survey Reference Region business
Zdroj:	Clinical Chemistry. 24:1744-1750
ISSN:	1530-8561 0009-9147
DOI:	10.1093/clinchem/24.10.1744
Popis:	We measured free thyroxine index, free triiodothyronine index, and thyrotropin in serum in a community survey of the female population 39--60 years old. A statistical method using Mahalanobis' distance was applied to the data, to identify and eliminate highly abnormal values, "outliers." There was a small but statistically significant increase in each of the three hormones with age. After correction for age dependency, significant but rather small correlations were found between the hormones. The material was used to calculate univariate reference intervals and a trivariate 0.95-tolerance region.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3469d6902f8217af4e4a4706e8804525 https://doi.org/10.1093/clinchem/24.10.1744 Zobrazit plný text záznamu