Concentration of nitrite and nonthiol nitroso compounds in tissues as a high sensitive marker of leukocyte activity
| Autor: | V. G. Vertiprakhov, V. Yu. Titov, O. B. Novikova, V.I. Fisinin, O. V. Kosenko, V. A. Petrov, M. E. Dmitrieva |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
chemistry.chemical_classification Reactive oxygen species Nitroso Compounds Chemistry 030111 toxicology Ros scavenger food and beverages Inflammation Cow milk 03 medical and health sciences Psychiatry and Mental health chemistry.chemical_compound 030104 developmental biology Neuropsychology and Physiological Psychology Blood chemistry Biochemistry Toxicity medicine medicine.symptom Nitrite |
| Zdroj: | Russian Agricultural Sciences. 43:423-426 |
| ISSN: | 1934-8037 1068-3674 |
| Popis: | This paper shows that the inflammation-induced appearance of nitrite and nonthiol nitroso compounds in the hen blood and cow milk is due to oxidation of dinitrosyl iron complexes (DNIC) and nitrosothiols (RSNO) by reactive oxygen species (ROS), which are produced by activated leukocytes. Since DNIC and RSNO are highly effective ROS scavengers, the content of nitrite and nonthiol nitroso compounds can be regarded as one of the most sensitive indicators of leukocyte activation. |
| Databáze: | OpenAIRE |
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