| Autor: |
Mei-yee Lau, Shuk-yu Leung, Ka-li Kwok, Daniel Kwok-Keung Ng |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Paediatric Sleep Medicine. |
| DOI: |
10.1183/23120541.sleepandbreathing-2019.p137 |
| Popis: |
Objective: Heated humidified high flow (HHHFNC) has gained its popularity in last decade but reports on its use in treating obstructive sleep apnea (OSA) in infants are scarce. Methods: Reports of all polysomnographic (PSG) titration studies done in infants ( Results: In this whole group of 13 infants, HHHFNC significantly reduced median obstrcutive apnea-hypopnea index (OAHI) from 10.9 events/h (IQR 5.0-28.4 events/h) to 0 events/h (0.6-1.7 events/h; P = 0.001); reduced median obstructive apnea index (OAI) from 7.3 events/h (IQR 1.6-14.7 events/h) to 0 events/h (0-0.6 events/h; P = 0.005); reduced median obstructive hypopnea index (OHI) from 4.4 events/h (IQR 0.6-8.8 events/h) to 0 events/h (0-0.7 events/h; P = 0.007); increased median SpO2 nadir from 89% (84% to 94%) to 94% (93% to 96%; P =0.041). The change in OAHI values had a negatively correlation with the flow/kg that significance (r=-0.589, p=0.034). HHHFNC alone achieved the abortion of the OSA in nine out of 13 patients, while 4 patients required the addition of oxygen. Stratified analysis of these 9 infants demonstrated that significant improvements in the OAHI, OAI and OHI. Conclusion: High-flow nasal cannula significantly reduces respiratory events and improves oxygenation. It is an effective treatment for infants with moderate to severe OSA. Our data suggest HHHFNC alone could effectively abort sleep apnea in 70% of patients under 1 year old. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
