Pulmonary metastasis in laryngeal squamous cell carcinoma
| Autor: | Uğur Temel, Gülpembe Bozkurt, Didem Rıfkı, Berna Uslu Coşkun, Senem Kurt Dizdar, Meltem Akpinar |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Oncology
medicine.medical_specialty business.industry Cancer Retrospective cohort study General Medicine Laryngeal squamous cell carcinoma medicine.disease 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Internal medicine medicine Pulmonary metastasis In patient Lymph Stage (cooking) 030223 otorhinolaryngology business Lymph node |
| Zdroj: | SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital. :303-8 |
| ISSN: | 1308-5123 1302-7123 |
| DOI: | 10.5350/semb.20160805021907 |
| Popis: | Objective: To identify the factors associated with pulmonary metastasis, such as lymph node positivity, tumour location and histological differentiation in patients with laryngeal squamous cell carcinoma (scc). Material and Methods: This study is designed as retrospective cohort study. Data from 263 patients diagnosed with laryngeal scc were reviewed retrospectively. Pulmonary metastasis was observed in 39 of these patients. Results: The transglottic tumors had the highest pulmonary metastasis rate (%50). The pulmonary metastasis rate was significantly lower in patients with glottic tumors than those with tumors in other regions (p= 0.003) The pulmonary metastasis rate was higher in lymph node-positive patients than in lymph node-negative patients. Pulmonary metastasis rate was significantly higher among patients with N2-N3 stage lymph nodes compared to those with N1 stage lymph nodes. Pulmonary metastasis rate is also increased significantly among patients with histologically poorly differentiated tumors (p= 0.001). Conclusion: The laryngeal cancer patients with positive lymph node, with transglottic tumour and with poorly/moderately differentiated tumour should be monitored carefully and followed up closely for possible pulmonary metastasis. |
| Databáze: | OpenAIRE |
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