The Transcription Activation of the RIG-I Gene Encoding the DEXH/D Protein in RH Cells Infected with Tick-Borne Encephalitis Virus

Autor:	M. B. Kostina, S. N. Konovalova, Elena V. Protopopova, A. V. Kachko, Eugene D. Sverdlov, Lev G. Nikolaev, Galina S. Monastyrskaya, Valery B. Loktev, O. B. Filyukova
Rok vydání:	2004
Předmět:	RIG-I Organic Chemistry Cell Biology medicine.disease biology.organism_classification Biochemistry Virology Molecular biology Embryonic stem cell Virus Tick-borne encephalitis virus medicine.anatomical_structure Suppression subtractive hybridization medicine Gene Encephalitis
Zdroj:	Russian Journal of Bioorganic Chemistry. 30:129-133
ISSN:	1068-1620
DOI:	10.1023/b:rubi.0000023097.29436.0f
Popis:	It was demonstrated by subtractive hybridization that the infection of a human embryonic kidney cell line with tick-borne encephalitis virus causes an approximately tenfold transcription activation of the RIG-I gene, which encodes a protein of the DEXH/D-box-containing RNA helicase family. A possible involvement of the protein in antiviral cell systems is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::344044fd3bfd578d638d74564490e176 https://doi.org/10.1023/b:rubi.0000023097.29436.0f Zobrazit plný text záznamu Full text from SpringerLink