An efficient one-pot synthesis of tetra-substituted pyrroles
Autor: | Elmira Ghabraie, Hamid Reza Bijanzadeh, Morteza Bararjanian, Saeed Balalaie, Frank Rominger |
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Rok vydání: | 2011 |
Předmět: |
chemistry.chemical_classification
biology Chemistry Organic Chemistry One-pot synthesis Nitro compound biology.organism_classification Biochemistry Chloride Medicinal chemistry Domino chemistry.chemical_compound One pot reaction Drug Discovery Michael reaction medicine Tetra Iron(III) chloride medicine.drug |
Zdroj: | Tetrahedron. 67:5415-5420 |
ISSN: | 0040-4020 |
Popis: | The three-component reaction of primary amines, dialkyl acetylenedicarboxylates and β-nitrostyrene derivatives in the presence of Iron(III) chloride afforded 1,2,3,4-tetra-substituted pyrroles in high yields. These reactions could precede via domino Michael addition/cyclization process. |
Databáze: | OpenAIRE |
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