Molybdenum hexacarbonyl mediated synthesis of indolin-2-one & azaindolin-2-one under catalyst free conditions

Autor: Arunendra Pathak, Shyam S. Pal, L. K. K. Reddy, Vikas S. Patil, Ramdas S. Pathare
Rok vydání: 2015
Předmět:
Zdroj: Tetrahedron Letters. 56:6370-6372
ISSN: 0040-4039
Popis: Syntheses of indolin-2-ones and azaindolin-2-ones have been realized. The strategy involves the formation of tosylhydrazone from tosylhydrazine and 2-amino aryl or pyridyl aldehydes/ketones which then undergo intramolecular aminocarbonylation to afford indolin-2-ones and azaindolin-2-ones. The generality of the method was demonstrated by synthesizing C3 substituted and unsubstituted indolin-2-one and azaindolin-2-one derivatives.
Databáze: OpenAIRE