Voltammetric study of the antioxidant properties of catalase and superoxide dismutase
| Autor: | O. I. Lipskikh, V. V. Ivanov, M. A. Kiseleva, E. I. Korotkova |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Pharmacology
chemistry.chemical_classification Reactive oxygen species Antioxidant biology medicine.diagnostic_test medicine.medical_treatment chemistry.chemical_element Copper Superoxide dismutase Enzyme chemistry Catalase Spectrophotometry Drug Discovery medicine biology.protein Voltammetry Nuclear chemistry |
| Zdroj: | Pharmaceutical Chemistry Journal. 42:485-487 |
| ISSN: | 1573-9031 0091-150X |
| DOI: | 10.1007/s11094-008-0156-0 |
| Popis: | The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms of the interaction of enzymes with reactive oxygen species are considered. Antioxidant activity criterion (IC 50 ) for SOD and some copper complexes have been estimated by voltammetry and spectrophotometry. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|