Size-Dependent Uptake and Distribution of AgNPs by Silkworms
| Autor: | Yingnan Zhu, Lei Zhang, Chiyu Wen, Jia Ke, Hongshuang Guo, Jiamin Zhang, Weiqiang Zhao, Jing Yang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Biodistribution
Biocompatibility Renewable Energy Sustainability and the Environment Chemistry General Chemical Engineering fungi technology industry and agriculture Nanoparticle macromolecular substances 02 engineering and technology General Chemistry equipment and supplies 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Silver nanoparticle 0104 chemical sciences Nanomaterials SILK Biophysics Environmental Chemistry 0210 nano-technology Antibacterial activity Natural fiber |
| Zdroj: | ACS Sustainable Chemistry & Engineering. 8:460-468 |
| ISSN: | 2168-0485 |
| DOI: | 10.1021/acssuschemeng.9b05799 |
| Popis: | Silk is an attractive natural fiber due to its excellent mechanical properties and biocompatibility. Xenobiotic modification of pristine silk is gaining significant attention to meet specific demands. The silk payload of xenobiotics is affected by their uptake efficiency, biodistribution, metabolism, and excretion. Herein, we systematically evaluated the effect of the nanoparticle size (20–100 nm) on the biodistribution and silk production by introducing silver nanoparticles (AgNPs) into the silkworm diet. Interestingly, the silk payload of AgNPs is highly dependent on their overall size, where 50 nm AgNPs are prone to accumulate in silk glands and reveal the highest content in the produced silk, qualifying silk antibacterial activity against both Gram-positive and Gram-negative bacteria. These findings provide new insights to understand how nanoparticle properties influence the incorporation of nanomaterials into silk and can help optimize the material design. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|