Successful lung transplantation with graft recovered after thoracoabdominal normothermic perfusion from donor after circulatory death
| Autor: | Heather M. Strah, Anthony W. Castleberry, M. Megan Chacon, Nicholas W. Markin, John Y. Um, Shaheed Merani, D.B. Berkheim, Aleem Siddique, Marian Urban |
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| Rok vydání: | 2022 |
| Předmět: |
Transplantation
Machine perfusion ARDS Lung business.industry medicine.medical_treatment Lung perfusion Acute respiratory distress respiratory system medicine.disease Circulatory death respiratory tract diseases Normothermic perfusion medicine.anatomical_structure Anesthesia Immunology and Allergy Medicine Lung transplantation Pharmacology (medical) business |
| Zdroj: | American Journal of Transplantation. 22:294-298 |
| ISSN: | 1600-6135 |
| DOI: | 10.1111/ajt.16806 |
| Popis: | Lung transplantation with lungs procured from donors after circulatory death (DCD) has been established as an alternative technique to traditional donation after brain death (DBD) with comparable outcomes. Recently, in situ thoracoabdominal normothermic regional perfusion (TA-NRP) has emerged as a novel technique employed in the procurement of cardiac allografts after circulatory death. TA-NRP, in contrast to ex situ machine perfusion, has the advantage of allowing in situ assessment of donor organs prior to final acceptance. However, there are some concerns that this technique may adversely impact the quality of lung allografts. Here, we present a case of a successful bilateral sequential lung transplantation in a patient with postinflammatory pulmonary fibrosis due to acute respiratory distress syndrome (ARDS), with lungs procured after normothermic in situ lung perfusion. Apart from the lungs, heart, liver, and kidneys were also successfully transplanted from this donor. |
| Databáze: | OpenAIRE |
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