Distribution of Neurochemical Deficits in Alzheimer’s Disease

Autor:	A. J. Cross, A. R. Green, Paul T. Francis, J. E. Steele, S. L. Lowe, G. C. Stratmann, David M. Bowen, A. W. Procter
Rok vydání:	1990
Předmět:	Glutamate receptor Neuropeptide Biology Inhibitory postsynaptic potential Phosphoglycerate mutase chemistry.chemical_compound Neurochemical chemistry Dopamine medicine Distribution (pharmacology) sense organs Neurotransmitter Neuroscience medicine.drug
Zdroj:	Imaging, Cerebral Topography and Alzheimer’s Disease ISBN: 9783642756924
Popis:	Cortical inhibitory neurotransmitters, neuropeptides, dopamine and probably noradrenaline are probably either not selectively or not critically affected in Alzheimer’s disease. It is, however, highly likely that shrinkage or loss of corticocortical pyramidal neurones is a key change. This change appears to be circumscribed and clinically relevant and to involve neurotransmitter glutamate. The putative pathogenic role of glutamate is briefly discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::33c0b32e30401e9f618fbaada740c705 https://doi.org/10.1007/978-3-642-75690-0_3 Zobrazit plný text záznamu