A convenient iodination of indoles and derivatives

Autor:	Salha Hamri, Gérald Guillaumet, M. Dolors Pujol, José Remesal Rodríguez, Joan Basset
Rok vydání:	2012
Předmět:	Indole test Electrophilic substitution chemistry.chemical_compound chemistry Reagent Yield (chemistry) Organic Chemistry Drug Discovery Halogenation Organic chemistry Biochemistry Pyrrole derivatives Iodine monochloride
Zdroj:	Tetrahedron. 68:6269-6275
ISSN:	0040-4020
DOI:	10.1016/j.tet.2012.05.053
Popis:	We report a direct iodination of indole and derivative compounds with iodine monochloride (ICl) in the presence of Celite ® . This procedure has now been extended to the iodination of substituted indoles, azaindoles and pyrroles. The scope of this procedure is exemplified by the iodination of melatonin in 98% yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::33bdef109005794e00ca631b63bf3bb5 https://doi.org/10.1016/j.tet.2012.05.053 Zobrazit plný text záznamu Full Text from ScienceDirect