The 130-kDa Vacuolating Cytotoxin-Associated Protein Is a Component of Cytotoxic Helicobacter pylori Organisms

Autor:	D Armellini, Rino Rappuoli, M Bugnoli, Natale Figura, Aldo Rossolini, Z Xiang
Rok vydání:	1994
Předmět:	biology Molecular mass Toxin Chemistry Helicobacter pylori biology.organism_classification medicine.disease_cause In vitro Microbiology Vacuolization medicine Cytotoxic T cell Gastritis medicine.symptom Intracellular
Zdroj:	Basic and Clinical Aspects of Helicobacter pylori Infection ISBN: 9783642782336
Popis:	Helicobacter pylori (HP) is the agent of type B gastritis and a cofactor in the development of peptic ulcer and probably also of gastric cancer. Certain HP strains produce a toxin which induces intracellular vacuolization on mammalian cells in vitro. Proteins associated with vacuolating activity (VA) have molecular weights of 130, 95, and 80 kDa and can be detected broth and in concentrated broth culture filtrates (CBCF) of cytotoxic strains [1].
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::33bad61dc542b48a50734b2acf87d06e https://doi.org/10.1007/978-3-642-78231-2_41 Zobrazit plný text záznamu