Synthesis and optical properties of novel Tröger's base derivatives
| Autor: | Sheng-liang Zhou, Zhang Peng, Shu-ying Huang, Hui Wu, Jiang-biao Xu, Jin-juan Liu, Ming-qi Li, Yuan Rui |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
010405 organic chemistry
Carbazole Organic Chemistry Diphenylamine 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry Fluorescence 0104 chemical sciences chemistry.chemical_compound Suzuki reaction chemistry Phenothiazine Drug Discovery Organic chemistry MTT assay Density functional theory Tröger's base |
| Zdroj: | Tetrahedron. 72:4081-4084 |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/j.tet.2016.05.042 |
| Popis: | Diphenylamine, phenothiazine or carbazole were introduced into Troger's base skeleton via Ullmann or Suzuki coupling to afford new TB derivatives. Their optical properties tests, density functional theory (B3LYP; 6-31G*) calculations were investigated. Incidentally anti-cancer activity against human hepatoma HepG2 cells in vitro (MTT assay) were investigated. All the results indicated that these novel compounds have the potential as fluorescence materials. |
| Databáze: | OpenAIRE |
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