STUDY OF THE COMPOSITION OF ESSENTIAL OIL ACHILLEA NOBILIS L. AND ITS ANTIBACTERIAL INFLU-ENCE ON CHANGE OF STAPHYLOCOCCUS AUREUS CELL ULTRASTRUCTURE
| Autor: | Fuad Guseynali ogly Rzayev, Yusif Balakerim ogly Kerimov, Sabina Alifaga kyzy Israfilova, Siradzheddin Veli ogly Serkerov, Sevda Agarakhim kyzy Muradova, El'vin Gadzhi ogly Karimli, El'dar Kochari ogly Kasumov |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
biology Achillea 030106 microbiology Organic Chemistry Achillea nobilis Plant Science biology.organism_classification law.invention Biomaterials 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology Eucalyptol chemistry law Ultrastructure Food science Thujone Lavandulol Antibacterial activity Essential oil |
| Zdroj: | chemistry of plant raw material. :93-104 |
| ISSN: | 1029-5143 1029-5151 |
| Popis: | The component composition of the Achillea. nobilis essential oil, which grows in Azerbaijan, was studied for the first time by the gas-chromato-mass spectrometry method. In the essential oil, 35 components are identified, of which the predominant are artemisia ketone (23.706%), thujone 22.400%), 2-bornanone (6,367%), eudesm-7(11)-en-4-ol (6.321%), eucalyptol (4.507%), cubenol (3.317%), lavandulol (2.975%), β-thujone (2.933%), β-eudesmol (2.702%), methyl hinokiate (2.108%), terpinen-4-ol (1.715%), 1,2-longidione (1.313%), limonene-6-ol, pivalate (1.188%), neryl (S)-2-methylbutanoate (1.120%), caryophyllene oxide (1.014%). The effect of A. nobilis essential oil on the ultrastructural organization of bacteria (S. aureus) was studied using transmission electron microscopy. It was revealed that under the influence of essential oil, a violation of the plasma permeability of the plasma membrane is observed, accompanied by diffusion of the fine-grained osmiophilic precipitate of the destroyed cytoplasmic structures, which leads to the loss of the layered structure of the wall elements and to a significant compaction of the matrix in comparison with the control preparations. The death of bacterial cells was observed with complete destruction of the integrity of all structures that make up their wall. Along with this, on ultrathin sections, focal accumulations of dead bacterial cells are found, surrounded by structurally changed elements of their walls. The remains of destructively altered fragments of CP are found on various parts of unseparated bacterial cells. All of the above shows that the essential oil of A. nobilis has a pronounced antibacterial activity. |
| Databáze: | OpenAIRE |
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