Cytopathogenic action ofEscherichia coli cells containing heterologous human type O(H) antigen on human cells in culture

Autor: N. I. Kochergina, G. M. Bochko, I. I. Podoplelov
Rok vydání: 1977
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 84:1002-1004
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00798530
Popis: The character of interaction between two enteropathogenic strains ofEscherichia coli of serotype 055∶K59 with human HeLa cells containing O(H) isoantigen was studied. On the addition of strainE. coli No. 5789, containing heterologous type O(H) antigen to a culture of HeLa cells, a cytopathogenic action was discovered on the third day of interaction in the presence of doses of bacterial cells of 2·1010, 2·105, and 2·104. A dose of 2·103 bacterial cells ofE. coli did not give this effect. Strain No. 3827, not containing heterologous antigen of ABO type, had no cytopathogenic action in maximal, average, and small doses of bacterial cells. It is suggested that the cytopathogenic action of strain No. 5789 is connected with the presence of an antigen in this strain which is identical with the group antigen of the human cell culture studied.
Databáze: OpenAIRE
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