Postpartum amenorrhea-galactorrhea of
| Autor: | M.C. Devlin, R.A.H. Kinch, E.R. Plunkett |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
endocrine system
Pediatrics medicine.medical_specialty Galactorrhea Pathology endocrine system diseases medicine.drug_class business.industry Urinary system Pituitary tumors Thyroid Postpartum amenorrhea Obstetrics and Gynecology medicine.disease Pathophysiology medicine.anatomical_structure Lactation medicine Gonadotropin medicine.symptom business |
| Zdroj: | American Journal of Obstetrics and Gynecology. 105:766-773 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/0002-9378(69)90012-x |
| Popis: | Recent studies of the control and function of the hypothalamic-pituitary complex have developed more interest in, and therefore disclosed more cases of, the amenorrhea-galactorrhea syndrome. Although some authors believe this to be a manifestation of pituitary chromophobe adenoma, analysis of series of such tumors rarely reveals pathologic lactation to be a prominent symptom. This paper reports 4 cases of the secondary amenorrhea-galactorrhea syndrome, puerperal in onset and hypothyroid-associated; 3 cases had low urinary gonadotropin levels and none had evidence of pituitary tumor. All patients responded rapidly and completely to simple thyroid replacement therapy. The authors suggest that the Chiari-Frommel syndrome is a symptomatic diagnosis, and that thyroid as well as pituitary pathology should be excluded as an etiologic factor. A multifactorial pathophysiology is offered and supporting evidence reviewed. |
| Databáze: | OpenAIRE |
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