Pathologically Normal Coronary Artery after Kawasaki Disease: A Case Report
| Autor: | Yasuhiro Ueno, Kei Takahashi, Shirou Naoe, Takashi Fukaya, Yasuhiko Tomita, Kunizo Baba |
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| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Pediatric Research. 53:174-174 |
| ISSN: | 1530-0447 0031-3998 |
| DOI: | 10.1203/00006450-200301000-00123 |
| Popis: | It is well known that the sequelae of the vasculitis are observed pathologically in the coronary arteries of the patients with Kawasaki disease. It has been reported that these abnormal findings are commonly detected even in patients with clinical diagnosis of normal coronary arteries. We experienced a case of Kawasaki disease without clinically and pathologically significant coronary artery lesions. A 1 year 0 month-old male infant had an episode of Kawasaki disease. The diagnosis was established from the 5 principal clinical findings except lymphadenopathy. He also had redness of the skin at the site of BCG inoculation. He was treated with intravenous gamma globurin(1g/kg) administered two times. Echocardiographic evaluation of the coronary artery was carried out several times during the acute phase of the illness until 2 months after the onset of the disease, and no abnormal findings were obtained. His clinical diagnosis was complete recovery from the Kawasaki disease. He died suddenly when he was 2 years 1 month old. He had a febrile episode at night, and in the next morning, he was found dead. From the macroscopic autopsy findings, the cause of the death was diagnosed as an acute bronchitis. Histologically, the coronary arteries had normal architecture, and no particular sequelae of arteritis were found. Scar formation was not detected. Mild intimal thickening was observed in the proximal portion of the bilateral coronary arteries, but it was not thought to be pathologically significant. Distal portion of the coronary arteries were normal. Myocarditis and myocardial ischemia were also excluded. From these findings, we concluded that there were patients with complete recovery from Kawasaki disease, not only clinically but also pathologically. This fact may influence the follow up methods of the patients with clinically complete recovery from Kawasaki disease. |
| Databáze: | OpenAIRE |
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